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PRP injections use platelet-rich plasma prepared from a patient’s own blood and are used or studied across selected musculoskeletal, hair-loss, and aesthetic indications. For musculoskeletal conditions, hair loss, or aesthetic concerns, expected benefit varies by diagnosis and treatment protocol. At our Beverly Hills clinic, Dr. David Nazarian, MD evaluates candidacy, discusses the evidence and alternatives, and tailors treatment to the individual patient.
PRP stands for platelet-rich plasma. This refers to a plasma solution with a concentrated plasma component. Platelet-rich plasma injections are an autologous procedure intended to deliver a concentrated platelet preparation to a targeted area; its role and supporting evidence vary by condition.
Plasma is the liquid component of our blood. The non-liquid or cellular component includes various blood cells like red blood cells, white blood cells, and platelets. Platelets contain beneficial proteins like insulin-like growth factor (IGF), platelet-derived growth factor (PDGF), and vascular endothelial growth factor (VEGF). All these factors perform important functions in forming a stable blood clot, stimulating cell growth and regeneration, and accelerating the healing process.
When creating platelet-rich plasma, a doctor takes the patient’s blood sample and runs it through a centrifuge. This device spins the sample at high speed to separate the different blood components. As a result, the fluid separates into three layers: the red blood cells settle at the bottom, platelets occupy the middle layer, and plasma rises to the top.
PRP is extracted from the middle layer, resulting in a plasma solution with a concentrated level of platelets. Normal platelet count in blood ranges between 150,000 and 350,000 platelets per milliliter. PRP preparation methods and platelet concentrations vary by device and protocol; there is no single concentration that is appropriate for every indication.
Due to its strong healing effects, platelet-rich plasma therapy can be used to treat different conditions ranging from orthopedic disorders to connective tissue healing. The most common therapeutic applications for PRP injections include musculoskeletal injuries, so they can be instrumental in sports medicine treatments.
PRP injections are used or studied for selected hair, musculoskeletal, and aesthetic indications. At our Beverly Hills clinic, the first step is determining whether PRP is appropriate for the diagnosis, what evidence applies to that indication, how many sessions may be considered, what recovery to expect, and what the treatment will cost. Common reasons patients ask about PRP include –
PRP is an all-natural treatment. It entails the patient’s blood, so no external drugs or chemicals are involved in the process, which may reduce some risks associated with donor-derived products. Patients receive an injection of their blood cells, so there’s a lower risk of immune reaction than donor-derived products, although injection-related risks still remain.
PRP injections are also less invasive than surgery. Within the first few days, patients may experience some discomfort around the injection site, but it’s usually mild, and it fades away.
Another advantage of PRP therapy is that it can treat a wide variety of symptoms. In addition to pain relief, PRP reduces inflammation and stiffness while targeting damaged tissues.
PRP is derived from your own blood and is autologous; thus, there should be no allergic reactions due to the injection. There may be some slight discomfort at the injection site and redness or bleeding, but the procedure is usually tolerated well without any issues.
There is not much preparation that is needed prior to platelet-rich plasma injections. It is advised that you do not be on Asprin or NSAIDs such as Advil or be on blood thinners prior to your procedure.
The first stage of PRP injection therapy is drawing a blood sample from the patient. Therefore, patients should be well-hydrated before their appointment. They should also have a meal beforehand to avoid feeling dizzy during the blood sampling procedure. Mild soreness at the injection site is a common side effect, but it usually diminishes within a few hours.
Several PRP injections are administered for optimal effect. The number of injections depends on the type of injury and affected area. Typically, patients receive one to three PRP injections. The gap between one injection and another is usually one month.
After your PRP therapy procedure, it is often recommended not to wash the area and let the PRP stay on for at least 24 hours. This is to ensure that the growth factors and proteins have a chance to heal the area they were injected or applied to.
Since PRP relies on the body’s natural healing mechanisms, it might take a few weeks for patients to feel the treatment’s complete effect. Over time, the injected plasma activates cells and tissues to heal and regenerate. The average success rate of PRP therapy is 80 percent. Usually, patients can notice the treatment effect after six to nine weeks. The therapeutic effect of PRP injections lasts for 6-9 months.
PRP injections can be helpful in promoting hair growth and skin healing. Patients who suffer from male pattern baldness are eligible to try PRP injections which can slow down hair loss. Doctors inject PRP directly into the scalp to improve blood supply to the growing hair follicles. As a result, PRP increases hair count and enhances follicle thickness.
Further, patients who undergo hair transplants can take PRP injections to improve hair growth after the operation. Postoperative PRP injections can improve hair regeneration and activate dormant hair follicles to grow new hair.
A review study published in Journal of Drug Des Devel Ther in 2022 revealed that PRP can be used as a new and effective therapeutic option for hair loss. It concluded that it was effective in treating androgenetic alopecia and female pattern hair loss, either by itself or with medications such as minoxidil and finasteride. It also found that PRP is considered a safe and effective way to treat alopecia areata and other hair loss disorders. The study also revealed that there was enough evidence showing that PRP can improve clinical symptoms in some types of cicatricial alopecia.
Some sports injuries like tennis elbow, Achilles tendon inflammation, jumper’s knee, rotator cuff pain, or hamstring muscle cramps respond very well to PRP injections. Unlike surgery, PRP injections are less invasive, making them less likely to put the patient at risk of bleeding, infection, or other postoperative complications. PRP treatment can also help athletes recover from sprains, strains, and other muscle injuries 50 percent faster than traditional options like physical therapy and medication.
PRP under-eye treatment may be considered for selected patients with hollowness or skin-quality concerns, but results vary and dark circles can have multiple causes. A clinical evaluation is important before deciding whether PRP, PRF, filler, or another approach is appropriate. This procedure is usually performed at the same time with microneedling and helps in the production of collagen and elastin. The stimulation of collagen and elastin by our bodies help fill the hollowness, tighten the skin, and decrease the dark appearance. Puffiness and discoloration are less after the treatment with improvement of bags.
Other orthopedic conditions that can be improved through the use of PRP injections include osteoarthritis. Once injected, PRP changes the environment around the inflamed joint, decreasing inflammation, pain, and stiffness.
An observational study published in Agri revealed that PRP injections provided a meaningful improvement in chronic knee pain in patients with knee OA throughout a 12-week period. The pain reduction response to PRP was higher in patients with early-stage knee OA.
A review article published in Therapeutic Advances in Chronic Disease in 2019 revealed that there was enough available evidence supporting the use of PRP therapy to treat Osteoarthritis. The results from randomized clinical trials seemed to favor PRP use over other intra articular treatments such as hyaluronic acid injections, to improve pain in the short and medium term (6–12 months).
Patients recovering from surgery can still benefit from PRP. PRP treatment can accelerate postsurgical recovery. Many people choose PRP injections to speed up their recovery after muscle and tendon surgery so they can resume daily activities without pain. Studies support using PRP injections to promote healing after tendon and ligament surgeries such as anterior cruciate ligament (ACL) operations.
PRP is also used in the form of vampire treatments for skin treatments. Platelets contain alpha granules which play a role in wound healing and enhance skin elasticity and texture. Doctors can inject PRP into the skin to remove wrinkles and deep creases. The treatment can reduce acne scars as well. PRP Facial can result in an even-toned skin complexion with a more youthful look.
PRP treatment Beverly Hills has been treating different conditions utilizing growth factors and cytokines found in platelet-rich plasma for 18 years. Platelet-rich plasma is full of cytokines and growth factors that help in the healing process. Our medical clinic has improved this therapy by improving the extraction and isolation of such growth factors and cytokines.
Our medical staff and doctor are very proficient in the use of PRP injections for facial rejuvenation. They have utilized various techniques and therapeutic modalities to obtain the best results for their patients. Our micro-needling alongside your PRP therapy will leave your skin feeling rejuvenated and looking its best.
A review article published in Acta Biomed in 2021 revealed that in 3 and 6 months follow-ups respectively, moderate to excellent improvement was seen in periorbital dark circles (47.8%,60.9%), periorbital wrinkles (73.9%,78.3%), nasolabial fold (52.2%,56.6%) and skin rigidity (52.3%,60.9%) were seen in patients who underwent PRP therapy. Best results were seen for periorbital dark circles and wrinkles.
Oftentimes, PRP can help with osteoarthritis and pain as a result of arthritis. Our doctor can examine you and review imaging test results to assess better if you are a good candidate for this therapy.
A review article published in arthroscopy in 2016 revealed that In patients with symptomatic knee osteoarthritis, PRP injection resulted in significant clinical improvements up to 12 months post injection. Clinical outcomes and The Western Ontario and McMaster Universities Arthritis Index scores were significantly better after PRP versus hyaluronic acid injections at 3 to 12 months post injection.
Yes, PRP is injected to help with meniscus tears and injuries. Our doctor can review your MRI results to see the extent of your meniscus tear and to better assess in regards to therapy. Some more serious meniscus injuries do require surgery to treat the tear properly.
A review article published in Journal of Orthopedic Surgery in 2022 revealed that meniscus repairs augmented with PRP led to significantly lower failure rates and better postoperative pain control compared with those of the non-PRP group.
Platelet-rich plasma therapy can help with a variety of conditions and ailments and often with great success and results. Patients undergoing PRP therapy are usually very satisfied with the outcome as their joint pain, tendon injury is improved, or hair is growing back thicker and fuller.
With hair restoration and thinning hair, the opportunity to grow fuller hair is priceless for many and less costly than a hair transplant. Below is the fee structure for our platelet-rich plasma therapy procedures and packages should you purchase a package of 3 PRP sessions.
List the different PRP services and packages:
To find out more about PRP injections, book an appointment at PRP Treatment Beverly Hills and set up your consultation with one of the medical providers. Our healthcare providers can perform a full physical examination and guide you through the PRP treatment process. PRP Treatment of Beverly Hills is the medical practice to trust for PRP injections for a variety of conditions.
We are conveniently located in Beverly Hills and serve patients from Beverly Hills and the greater Los Angeles area.
Book now at 844-669-0939
9301 Wilshire Blvd Suite 405
Beverly Hills, CA 90210
References
1. Paichitrojjana A, Paichitrojjana A. Platelet Rich Plasma and Its Use in Hair Regrowth: A Review. Drug Des Devel Ther. 2022 Mar 10;16:635-645. doi: 10.2147/DDDT.S356858. PMID: 35300222; PMCID: PMC8922312.
2. Paichitrojjana A, Paichitrojjana A. Platelet Rich Plasma and Its Use in Hair Regrowth: A Review. Drug Des Devel Ther. 2022 Mar 10;16:635-645. doi: 10.2147/DDDT.S356858. PMID: 35300222; PMCID: PMC8922312.
3. Gato-Calvo L, Magalhaes J, Ruiz-Romero C, Blanco FJ, Burguera EF. Platelet-rich plasma in osteoarthritis treatment: review of current evidence. Ther Adv Chronic Dis. 2019 Feb 19;10:2040622319825567. doi: 10.1177/2040622319825567. PMID: 30815245; PMCID: PMC6383098.
4.Banihashemi M, Zabolinejad N, Salehi M, Hamidi Alamdari D, Nakhaizadeh S. Platelet-rich Plasma use for facial rejuvenation: a clinical trial and review of current literature. Acta Biomed. 2021 May 12;92(2):e2021187. doi: 10.23750/abm.v92i2.9687. PMID: 33988167; PMCID: PMC8182581.
5. Meheux CJ, McCulloch PC, Lintner DM, Varner KE, Harris JD. Efficacy of Intra-articular Platelet-Rich Plasma Injections in Knee Osteoarthritis: A Systematic Review. Arthroscopy. 2016 Mar;32(3):495-505. doi: 10.1016/j.arthro.2015.08.005. Epub 2015 Oct 1. PMID: 26432430.
6. Li Z, Weng X. Platelet-rich plasma use in meniscus repair treatment: a systematic review and meta-analysis of clinical studies. J Orthop Surg Res. 2022 Oct 8;17(1):446. doi: 10.1186/s13018-022-03293-0. PMID: 36209223; PMCID: PMC9548158.
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