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PRP Vs PRF - PRP Treatment

If you’re seeking PRF injection treatments in Beverly Hills, consider scheduling a consultation with our experienced professionals at PRP Treatment Beverly Hills clinic. With a focus on patient care and personalized treatment plans, our team can help determine if PRF injections are a suitable option for your specific condition.

We offer PRF injections and regenerative medicines for hair loss and growth, microneedling skin rejuvenation, osteoarthritis, joint pain, tendonitis, muscle injuries, scars, stretch lines, fine lines, under-eye dark circles, volume loss, acne scars, and more. Our medical center also offers stem cell therapies, PRP, and other regenerative therapies.

Platelet-rich plasma (PRP) is a treatment that can help with a variety of conditions including muscle and bone problems. So far, studies have shown that PRP is safe to use [1].

What is Platelet-rich plasma (PRP)?

Platelet-rich plasma (PRP) is a composition of two components: plasma, the natural liquid portion of blood, and platelets, which are known for their capacity to clot. In addition to this common knowledge about platelets’ remarkable anticoagulant (clotting) abilities, they also house growth factors that can trigger cell reproduction and stimulate tissue regeneration or healing in certain locations – such as facial acne scars – when used therapeutically.

To produce platelet-rich plasma, medical practitioners take a specimen of blood from their patient and subject it to centrifugation technology within a device such as ultrafiltration. The resulting supernatant is rich in platelets – thereby allowing for enhanced treatment options for patients.

What is a PRP Injection?

Platelet-rich plasma (PRP) is made from the patient’s blood and is injected into the area that needs to heal. This could be the knees, scalp, tendons, or joints. Sometimes, PRP specialists use ultrasound to help them inject the PRP in the right place. PRP injections contain more of certain helpful substances like specific proteins or hormones (growth factors) that can make the healing process faster.

It’s not entirely clear how PRP injections work, but one research suggests that patients with knee osteoarthritis who receive a PRP injection experience significant improvement in their symptoms for up to 12 months after the injection [2].

What are the Most Common Types of PRP?

The classification of platelet concentrates can be in 4 types. Pure PRP, L-PRP, Pure PRF, and L-PRF.

This classification was first proposed in 2009 and is now widely cited as a milestone in the classification terminology [3].

Here are two types of PRP according to the classification:

  • Pure Platelet-Rich Plasma or Pure PRP (P-PRP) – P-PRP is made by taking out all of the white blood cells and reducing the amount of fibrin. It can be given as a liquid injection or applied as a gel.
  • Leukocyte and Platelet-Rich Plasma (L-PRP) – L-PRP maintains its leukocyte count but with a low fibrin matrix. It is similar to P-PRP, where it is commercially available in liquid solutions or activated topical products.

Benefits of PRP


Stimulate Collagen Production

Collagen is a critical protein for maintaining youthful skin, hair, and nails. As we grow older, our bodies synthesis of collagen declines. This can lead to wrinkles and fine lines as well as sagging skin. PRP injections provide a viable solution through the use of growth factors that can enhance collagen production in order to produce a firmer and more resilient-looking epidermis.

Improves Erectile Function

Erectile dysfunction (ED) is a common condition in which a man has difficulty achieving or maintaining an erection. PRP injections can be used to improve blood flow to the penis, which helps to improve erectile function in men with ED. A study showed that PRP injections might be a promising treatment for ED management [4].

Improves Sagging Skin

PRP treatment can help reverse signs of aging and saggy skin. By penetrating deep into the skin, it stimulates collagen production and connective tissue regeneration. As a result, the skin will appear taut and lifted. Plasma-rich platelet therapy, in combination with fractional CO2 laser, microneedling, and microdermabrasion, can improve skin texture.

Reduces Hyperpigmentation

Hyperpigmentation can be managed through microneedling with platelet-rich plasma. Microneedling creates tiny holes in the skin to promote collagen production. In addition, issues such as scar hyperpigmentation and sun spots (melasma) can also be remedied by PRP therapy.

Helps Reduce Acne Scars

Helps reduce acne scars - PRP Treatment

PRP treatment can help reduce scars caused by acne. The injection contains a concentration of platelets, stem cells, growth factors like specific bio-proteins or hormones, and other elements containing neo-collagenases. PRP injections can also cure skin depression and stimulate collagen production.

Improve Hair Health

PRP injections can facilitate the body’s natural healing process. The injection can reduce hair loss and increase hair volume and density. A 2015 study states that PRP treatment facilitated hair growth in men more than in those who did not receive it [5].

Side Effects of PRP

  • Pain and discomfort
  • Swelling
  • Bruising
  • Allergic reaction
  • Nerve damage
  • Bleeding
  • Infection

What is PRF?

Platelet-rich fibrin (PRF) is another type of platelet concentrate treatment. The fibrin matrix contains platelet cytokines, growth hormones, and cells to promote skin rejuvenation and wound healing. Using the concentration of your own blood sample, the therapy can be an effective way of treating the texture and appearance of the skin. The injection promotes collagen growth. a combination of hyaluronic acid filler with PRF can be used for increased advantage.

What are the Most Common Types of PRF?

Here are two types of PRF according to the classification:

  • Pure Platelet-Rich Fibrin (P-PRF) – Leukocyte-Poor Platelet-Rich Fibrin or P-PRF are leukocyte-less concentrates with a high-density fibrin network. P-PRF only exists in gel form and can’t be injected or used like fibrin glues.
  • Leukocyte- and Platelet-Rich Fibrin (L-PRF) – L-PRF is a concoction of concentrates of leukocytes (white blood cells) and a high-density fibrin network. It can only be used in strongly activated gel form. This can’t be used as an injection or like traditional fibrin glues [6].

Benefits of PRF


Accelerates Healing Time

PRF has healing factors that can be used to speed up the healing process. It was used in dentistry procedures before but now has slowly become popular for facial esthetics. The platelet contents held by the fibrin matrix accelerate the healing process and regeneration of natural tissue.

Reduction of Fine Lines and Wrinkles

PRF therapy can be a great alternative to botox, dermal fillers, and mesotherapy as it improves fine lines and wrinkles and has anti-aging benefits. The therapy provides higher platelet concentration while maintaining the fibrin matrix minus the anticoagulants.

Improves Under-eye Hollows

To improve fine lines and under-eye hollows, PRF treatment can be used. While anti-aging creams and serums can help, PRF works wonders for reducing the appearance of eye wrinkles, fine lines, and rejuvenating skin.

Little to no Side Effects

Unlike synthetic fillers, your body won’t recognize this as foreign material. Therefore, there are little to no side effects. This is because the platelets concentrate is obtained from your own blood vessels.

Side effects of PRF

  • Redness of skin
  • Bruising or pain
  • Puffiness under the eyes can be observed but lasts for 4-5 days
  • Swelling

What is the Difference Between PRF vs PRP?

PRP is a process where blood is spun really fast in a tube to separate heavier cells like white blood cells and stem cells from lighter plasma and platelets. The platelets and plasma are then collected and injected into the injured area.

On the other hand, PRF is spun at a lower speed so that layers of blood are not distinctly separated. This allows some white blood cells and stem cells to remain in the platelet layer for treatment, which means there are more healing factors than in PRP. Moreover, a lower spin speed causes less damage to the cells of the blood and allows more stem cells to remain in the final PRF product.

Another difference is that PRP uses acid-citrate dextrose (ACD), an anticoagulant, to keep the blood from clotting too quickly in test tubes, while PRF tubes do not have anticoagulants. The purpose of not using anticoagulants in PRF is to keep the platelet product as natural as possible.

Does PRF last longer than PRP?

PRF may last longer than PRP in terms of the release of growth factors and healing factors over time. This is because PRF contains a higher concentration of growth factors and cytokines compared to PRP. Additionally, the fibrin matrix in PRF provides a scaffold for cell migration and tissue regeneration, which may contribute to longer-lasting effects.

What is Better, PRF or PRP?

PRF is considered more effective than PRP because it provides the same benefits as PRP and also releases more growth factors over time. This means that it continues to work even after the procedure is completed.

PRF & PRP Treatment Near Me

PRP Treatment Beverly Hills offers the best PRF & PRP treatment near me in Beverly Hills but can also come to your home or office throughout the Los Angeles area. We serve patients near Beverly Hills, Bel Air, West Hollywood, Santa Monica, West Los Angeles, Culver City, Hollywood, Venice, Marina del Rey, Malibu, Manhattan Beach, Redondo Beach, Downtown Los Angeles, Encino, Woodland Hills, Sherman Oaks, Calabasas, Burbank, Glendale, Hidden Hills, Agoura Hills, Northridge, North Hollywood, Topanga, Canoga Park, Reseda, Valley Glen, Chatsworth, West Hills, Winnetka, Universal City, Silverlake, Echo Park, and many more.


1. Le ADK, Enweze L, DeBaun MR, Dragoo JL. Platelet-Rich Plasma. Clin Sports Med. 2019;38(1):17-44. doi:10.1016/j.csm.2018.08.001

2. Meheux CJ, McCulloch PC, Lintner DM, Varner KE, Harris JD. Efficacy of Intra-articular Platelet-Rich Plasma Injections in Knee Osteoarthritis: A Systematic Review. Arthroscopy. 2016;32(3):495-505. doi:10.1016/j.arthro.2015.08.005

3. Dohan Ehrenfest DM, Andia I, Zumstein MA, Zhang CQ, Pinto NR, Bielecki T. Classification of platelet concentrates (Platelet-Rich Plasma-PRP, Platelet-Rich Fibrin-PRF) for topical and infiltrative use in orthopedic and sports medicine: current consensus, clinical implications and perspectives. Muscles Ligaments Tendons J. 2014;4(1):3-9. Published 2014 May 8.

4. Poulios E, Mykoniatis I, Pyrgidis N, et al. Platelet-Rich Plasma (PRP) Improves Erectile Function: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial. J Sex Med. 2021;18(5):926-935. doi:10.1016/j.jsxm.2021.03.008

5. Gentile P, Garcovich S, Bielli A, Scioli MG, Orlandi A, Cervelli V. The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial. Stem Cells Transl Med. 2015;4(11):1317-1323. doi:10.5966/sctm.2015-0107

6. Dohan Ehrenfest DM, Andia I, Zumstein MA, Zhang CQ, Pinto NR, Bielecki T. Classification of platelet concentrates (Platelet-Rich Plasma-PRP, Platelet-Rich Fibrin-PRF) for topical and infiltrative use in orthopedic and sports medicine: current consensus, clinical implications and perspectives. Muscles Ligaments Tendons J. 2014;4(1):3-9. Published 2014 May 8.

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