Written and medically reviewed by David Nazarian, MD — Board Certified in Internal Medicine and Medical Director of PRP Treatment Beverly Hills. Last medically reviewed: October 2026.
Quick answer: PRP injections have been studied experimentally for female stress urinary incontinence, but evidence remains limited and does not replace established evaluation or treatments such as pelvic-floor muscle therapy, pessary options, or surgery when appropriate.
What is stress urinary incontinence?
Stress urinary incontinence is leakage with activities that increase abdominal pressure, such as coughing, laughing, sneezing, running, or lifting. It is different from urgency incontinence, although some women have both.
What has PRP research found?
A systematic review identified several small studies of periurethral PRP for female stress urinary incontinence. Some reported improvement in symptom scores, but evidence quality was low. In the randomized study included in that review, midurethral sling surgery produced stronger outcomes than PRP on several validated measures.
Why the diagnosis matters
Urinary leakage can result from stress incontinence, overactive bladder, infection, pelvic organ prolapse, neurologic disease, medication effects, or a combination. Treatment depends on the type and severity.
Established options
Pelvic-floor muscle training is often a first-line approach. Other options can include pessaries, continence devices, urethral bulking agents, or surgical procedures depending on the patient. PRP should be discussed only with clear counseling that it remains investigational.
See our PRP for female sexual dysfunction overview.
Important: PRP for sexual-function concerns is investigational/off-label. Evidence is limited and heterogeneous, and PRP should not be presented as a proven cure or replacement for established evaluation and treatment.
